UNIV - Research Nurse Manager - Hollings Cancer Center
Company: Medical University of South Carolina
Location: Charleston
Posted on: April 1, 2026
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Job Description:
Job Description Summary The Hollings Cancer Center (HCC) Nurse
Manager II is responsible for the provision of nursing education
and mentorship to the non-nursing staff HCC Clinical Trials Office
(CTO) and serves as a liaison to other clinical services and
providers within HCC outpatient and inpatient clinics, the HCC
infusion center, and other ancillary departments. Entity Medical
University of South Carolina (MUSC - Univ) Worker Type Employee
Worker Sub-Type? Classified Cost Center CC001331 HCC Administration
CC Pay Rate Type Salary Pay Grade University-CLN10 Pay Range
67,400.00 - 94,300.00 - 121,300.000 Scheduled Weekly Hours 40 Work
Shift Job Description The Hollings Cancer Center (HCC) Nurse
Manager II is responsible for the provision of nursing education
and mentorship to the non-nursing staff HCC Clinical Trials Office
(CTO) and serves as a liaison to other clinical services and
providers within HCC outpatient and inpatient clinics, the HCC
infusion center, and other ancillary departments. This position
will be part of the CTO Clinical Operations Unit and will report to
the Deputy Director of the Clinical Trials Office. This individual
must work collaboratively with CTO managers and ancillary services
in program development and strategic planning- which includes
participating in the organization and management of the new 3rd
Floor HCC Research Infusion Suite and expansion of research
services to satellite sites. This individual will participate in
the feasibility review process by reviewing protocols and
determining the study patient flow and provision of center
resources to promote protocol compliance and study participant
retention. Additionally, this nurse manager II will collaborate
closely with other clinical operation program managers and the
EPIC/Beacon build team members to ensure that study treatment plans
are built in accordance with the protocol for newly activated and
amended therapeutic protocols. The Nurse Manager II will have a key
role in helping train and mentor new study coordinators and data
managers in understanding oncology terminology and concepts. This
individual must be knowledgeable of Food and Drug Administration
federal regulations, local regulatory agency policies, and
international Good Clinical Practice Guidelines to ensure that the
conduct of clinical research activities remain in good standing and
research performance excels in quality and efficiency. Responsible
for the establishment of clinical operation standard operating
procedures and proper training and quality assurance initiatives.
Responsibilities: (35%) Protocol Implementation and Support:
Participates within the HCC CTO Research Allocation and Feasibility
Team (RAFT) to read protocols and develop the best method for
protocol implementation. Responsible for facilitating the
interaction between HCC’s clinical research program and the
clinical service line components. When complex trials are
identified by the RAFT and the HCC clinical research groups (CRG)
that require additional nursing resources greater that what is
provided as standard of care, this individual may be assigned to
the study and provide study specific nursing services such as ECOG
performance status assessments, vitals, EKGs, etc. Additionally,
the nurse manager will collaborate closely with other clinical
operation program managers. They will participate as a member of
the CTO EPIC/Beacon build team and ensure that study treatment
plans are built in accordance with the protocol for newly activated
and amended therapeutic protocols. This individual will review
study specific roadmaps to ensure that roadmaps are developed per
the protocol and operational assessment determined by the CRG. Will
lead the Beacon build validation meetings. Will review protocol
amendments and make changes to the roadmap as needed and per
standard operating procedures. Utilizes CTO systems such as
SharePoint and OnCore to mark milestone updates. As new protocol
amendments are released, re-evaluates the protocol for feasibility
and works with the clinical operations group to make adjustment to
study operations, allocation of resources and modification of study
source documents as needed. If protocol deviations are identified
due to Treatment Plan deficiencies, works with the CTO EPIC Beacon
team to correct roadmaps, and update treatment plans and re-educate
study coordinator and investigators as needed (35%) Protocol
Specific Clinical Operations Support: Reviews new protocols and new
amendments with the study coordinators to ensure proper
understanding of the investigational interventions and protocol
requirements. Assists with protocol-specific training of all
clinic, ancillary and program staff. May develop and conduct
educational in-services to interdisciplinary care teams to foster
protocol compliance. May work with the HCC nurse navigators to
market trials and assist them and the study coordinators in the
best method and timeframe to identify potential study patients.
Helps develop eligibility criteria source document tools and other
study specific source documents to improve protocol compliance and
adherence to the FDA Code of Federal regulations and Good Clinical
Practice Guidelines. When studies are activated and patients are
enrolled, works with the study coordinator and care team to ensure
tests and/or procedures are completed as required, results are
reviewed, correctly interpreted, and communicated with regards to
protocol guidelines and appropriate interventions occur based on
test results. In collaboration with the clinical operations
manager, conducts frequent meetings with the study coordinators to
ensure patients are appropriately linked to validated treatment
plans. Will help direct study coordinators with general patient
screening and protocol treatment questions. Will help teach study
coordinators the requirements related to grading toxicities and
communicating dose modifications requirements to study coordinator
and investigators. (25%) Quality Assurance and Education: Provide
mentorship and education for study coordinators who help oversee
study patient participation and help ensure protocol compliance.
This position will conduct the patient eligibility reviews required
prior to patient registration to the study to ensure that all
source documents are present per protocol and federal regulations.
Will utilize the patient eligibility reviews as a means for
additional one-on-one training with the study coordinator and
clinical staff or development of specific educational programs and
trainings to support greater clinical trial education and
compliance. Will provide general medical terminology training to
study coordinators and data managers and serves as a day-to-day
clinical resource to the clinical operations study coordinators and
data managers for assistance with understanding and interpreting
clinical documents, language, and patient process. Will develop
education materials and conduct new employee and advanced employee
clinical operations trainings. (5%) Special Projects and Additional
Duties: Provide project management of special activities.
Additional Job Description Minimum Requirements: Graduation from an
accredited school of nursing and five years related nursing
experience. A bachelor's degree in nursing may be substituted for
two years of the required work experience. Licensure as a
Registered Nurse by the South Carolina Board of Nursing. Some
positions require certification as a generalist in a related
specialty area by the American Nurses Association (ANA). Requires
certification in Basic Life Support. Physical Requirements: (Note:
The following descriptions are applicable to this section:
Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift;
Infrequent - 0-2 hours per shift) Ability to perform job functions
in an upright position. (Continuous) Ability to perform job
functions in a seated position. (Infrequent) Ability to perform job
functions while walking/mobile. (Frequent) Ability to climb stairs.
(Infrequent) Ability to climb ladders. (Infrequent) Ability to work
indoors. (Continuous) Ability to work from elevated areas.
(Infrequent) Ability to work in confined/cramped spaces.
(Infrequent) Ability to perform job functions from kneeling
positions. (Infrequent) Ability to bend at the waist. (Frequent)
Ability to twist at the waist. (Frequent) Ability to squat and
perform job functions. (Infrequent) Ability to perform 'pinching'
operations. (Infrequent) Ability to fully use both hands/arms.
(Continuous) Ability to perform repetitive motions with
hands/wrists/elbows and shoulders. (Frequent) Ability to fully use
both legs. (Continuous) Ability to reach in all directions.
(Continuous) Possess good finger dexterity. (Continuous) Ability to
maintain tactile sensory functions. (Continuous) Ability to
maintain good olfactory sensory function. (Continuous) Ability to
lift and carry 50 lbs., unassisted. (Frequent) Ability to lift
objects, up to 50 lbs., from floor level to height of 36 inches,
unassisted. (Frequent) Ability to lower objects, up to 50 lbs.,
from height of 36 inches to floor level, unassisted. (Frequent)
Ability to lift and carry patients weighing up to 350 lbs.,
assisted. (Frequent) Ability to push/pull objects, up to 350 lbs.,
unassisted. (Frequent) Ability to maintain 20/40 vision, corrected.
(Continuous) Ability to see and recognize objects close at hand.
(Continuous) Ability to see and recognize objects at a distance.
(Continuous) Ability to match or discriminate between colors.
(Continuous) Ability to determine distance/relationship between
objects; depth perception. (Continuous) Good peripheral vision
capabilities. (Continuous) Ability to maintain hearing acuity, with
correction. (Continuous) Ability to hear and understand whispered
conversations at a distance of 3 feet. Ability to perform gross
motor functions with frequent fine motor movements. (Continuous)
Ability to be qualified physically (by medical personnel) for
respirator use, initially and annually. Additional New
Requirements: Ability to deal effectively with stressful
situations. Computer literacy. Ability to work rotating shifts.
Ability to work overtime as required. Ability to learn and use new
processes, tools and equipment as required. If you like working
with energetic enthusiastic individuals, you will enjoy your career
with us! The Medical University of South Carolina is an Equal
Opportunity Employer. MUSC does not discriminate on the basis of
race, color, religion or belief, age, sex, national origin, gender
identity, sexual orientation, disability, protected veteran status,
family or parental status, or any other status protected by state
laws and/or federal regulations. All qualified applicants are
encouraged to apply and will receive consideration for employment
based upon applicable qualifications, merit and business need.
Medical University of South Carolina participates in the federal
E-Verify program to confirm the identity and employment
authorization of all newly hired employees. For further information
about the E-Verify program, please click here:
http://www.uscis.gov/e-verify/employees
Keywords: Medical University of South Carolina, Goose Creek , UNIV - Research Nurse Manager - Hollings Cancer Center, Healthcare , Charleston, South Carolina